Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL29089975

FC(F)[C@H](F)c1ccc(Br)cc1.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.37
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 4/20 0.33
ALOX15 P16050 2/20 0.33
MAPK1 P28482 2/20 0.33
CNR1 P21554 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP19A1 P11511 1/20 0.32
DPP4 P27487 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2C19 P33261 1/20 0.31
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29090004 1.00 CYP2A6 (0.42) CYP2A6HTR2ACYP1A2ALDH1A1ALOX15
Ammonia Solution, Strong SCHEMBL29089969 1.00 CYP2A6 (0.42) CYP2A6HTR2ACYP1A2ALDH1A1ALOX15
SCHEMBL28920988 0.97 CYP2A6 (0.44) CYP2A6HTR2ACYP1A2ALDH1A1ALOX15
SCHEMBL7670364 0.83 PGK1 (0.35)
Ammonia Solution, Strong SCHEMBL29248173 0.74 TSHR (0.44) CYP2A6ALDH1A1MAPK1CNR1CYP19A1
Hydrochloric Acid SCHEMBL29248508 0.74 IDO1 (0.44) HTR2ACYP1A2ALDH1A1CYP19A1CYP2D6
SCHEMBL11578 0.72 SLC6A2 (0.42) CYP2A6HTR2ACYP1A2ALOX15CNR1
SCHEMBL2131604 0.72 SLC6A2 (0.42) CYP2A6HTR2ACYP1A2ALOX15CNR1
SCHEMBL31582594 0.72 HTR2A (0.40) CYP2A6HTR2ACYP1A2ALDH1A1ALOX15
SCHEMBL4502164 0.72 HTR2A (0.40) CYP2A6HTR2ACYP1A2ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116916924-A MALT1 modulators and uses thereof 稀有生物科学股份有限公司 2023-10-20 CN disclosed