Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30547017 | 1.00 | TRPV1 (0.47) | TRPV1MTNR1AAOC3BRD4MTNR1B | |
| SCHEMBL29090130 | 0.88 | MTNR1A (0.46) | TRPV1MTNR1AMTNR1BHTR2CMCL1 | |
| SCHEMBL30547018 | 0.88 | MTNR1A (0.46) | TRPV1MTNR1AMTNR1BHTR2CMCL1 | |
| SCHEMBL6797799 | 0.86 | SLC6A2 (0.47) | MTNR1AAOC3MTNR1BL3MBTL1MEN1 | |
| SCHEMBL30547026 | 0.82 | TRPV1 (0.44) | TRPV1MTNR1AMTNR1BMCL1 | |
| SCHEMBL29090136 | 0.82 | TRPV1 (0.44) | TRPV1MTNR1AMTNR1BMCL1 | |
| SCHEMBL30547020 | 0.81 | MCL1 (0.44) | TRPV1MCL1MEN1KMT2ARAB9A | |
| SCHEMBL29090117 | 0.81 | MCL1 (0.44) | TRPV1MCL1MEN1KMT2ARAB9A | |
| SCHEMBL30547016 | 0.79 | GFER (0.51) | TRPV1MTNR1ABRD4L3MBTL1MCL1 | |
| SCHEMBL29090123 | 0.79 | GFER (0.51) | TRPV1MTNR1ABRD4L3MBTL1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730814-A | Novel naphthoquinone intermediate, preparation method thereof, chiral naphthalene compound and preparation method thereof | 香港科技大学深圳研究院 | 2023-09-12 | — | — | CN | disclosed |