Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | FABP4 | P15090 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594162 | 1.00 | LMNA (0.72) | LMNAMAPK1FABP4HDAC3HDAC1 | |
| SCHEMBL9489991 | 0.91 | NAMPT (0.70) | LMNAHDAC3HDAC1NAMPTMEN1 | |
| SCHEMBL9491028 | 0.91 | NAMPT (0.70) | LMNAHDAC3HDAC1NAMPTMEN1 | |
| SCHEMBL30481056 | 0.85 | LMNA (0.72) | LMNAMAPK1HDAC3HDAC1NAMPT | |
| SCHEMBL5657986 | 0.85 | LMNA (0.72) | LMNAMAPK1HDAC3HDAC1NAMPT | |
| SCHEMBL10865398 | 0.84 | MAPK1 (0.86) | LMNAMAPK1HDAC3HDAC1CYP1A2 | |
| SCHEMBL10659200 | 0.84 | MAPK1 (0.86) | LMNAMAPK1HDAC3HDAC1CYP1A2 | |
| SCHEMBL1231651 | 0.84 | MAPK1 (0.86) | LMNAMAPK1HDAC3HDAC1CYP1A2 | |
| SCHEMBL5655215 | 0.84 | MAPK1 (0.86) | LMNAMAPK1HDAC3HDAC1CYP1A2 | |
| SCHEMBL21320455 | 0.84 | LMNA (0.70) | LMNAMAPK1FABP4HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116897206-A | Oral delivery of PCSK 9-targeting antisense conjugates | 四纬生物制药股份有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-117545509-A | Oral delivery of oligonucleotides | 四纬生物制药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116897206-A | Oral delivery of PCSK 9-targeting antisense conjugates | 四纬生物制药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |