Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604191 | 1.00 | LMNA (0.40) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL30604218 | 1.00 | LMNA (0.40) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL29681204 | 1.00 | LMNA (0.40) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL24532840 | 1.00 | LMNA (0.40) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL29681155 | 1.00 | LMNA (0.40) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL24532735 | 1.00 | LMNA (0.40) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL24532496 | 0.92 | LMNA (0.42) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL30604113 | 0.92 | LMNA (0.42) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL24532144 | 0.89 | MAPT (0.44) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL24532138 | 0.88 | DPP4 (0.40) | LMNAKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |