SCHEMBL2909111

SCHEMBL2909111

C=C(C)C(=O)OC(C(=O)O)C(OC(=O)C(=C)C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 5/20 0.41
TP53 P04637 1/20 0.35
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
THRB P10828 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP13 P45452 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
TGFBR1 P36897 1/20 0.33
ELANE P08246 1/20 0.32
HSD17B10 Q99714 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL18440869 0.91 TSHR (0.41) ALDH1A1TSHRTP53SLC1A3SLC1A2
SCHEMBL18141689 0.87 ALDH1A1 (0.39) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
Ammonia Solution, Strong SCHEMBL18139731 0.85 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL28190009 0.85 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL7769789 0.85 SLC1A3 (0.52) ALDH1A1TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL28612220 0.82 TSHR (0.37) ALDH1A1TSHRTHRBMMP1MMP2
SCHEMBL13078898 0.82 TSHR (0.34) ALDH1A1TSHRTGFBR1
SCHEMBL17402240 0.80 TDP1 (0.45) ALDH1A1TSHRTHRBMMP1MMP2
SCHEMBL22471997 0.80 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTDP1TGFBR1
SCHEMBL8415532 0.80 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTDP1TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4543371-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1985-09-24 US claimed
US-4379864-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1983-04-12 US claimed
US-4267295-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1981-05-12 US claimed
US-20200360242-A1 Oral Care Gel COLGATE-PALMOLIVE COMPANY (US) 2020-11-19 US disclosed
US-10011746-B2 Radical curable adhesive composition and polarizing plate comprising same LG CHEM, LTD. (KR) 2018-07-03 US disclosed
US-9971066-B2 Polarizing plate LG CHEM, LTD (KR) 2018-05-15 US disclosed
US-9611411-B2 Radically curable adhesive composition and polarizing plate including the same LG CHEM, LTD. (KR) 2017-04-04 US disclosed
US-9611411-B2 Radically curable adhesive composition and polarizing plate including the same LG CHEM, LTD. (KR) 2017-04-04 US disclosed
US-9599753-B2 Polarizing plate LG CHEM, LTD. (KR) 2017-03-21 US disclosed
US-9599753-B2 Polarizing plate LG CHEM, LTD. (KR) 2017-03-21 US disclosed
US-9550918-B2 Radically curable adhesive composition and polarizing plate including the same LG CHEM, LTD. (KR) 2017-01-24 US disclosed
US-4401372-A Contact lens SYNTEX (U.S.A.) INC. (US) 1983-08-30 US disclosed
US-4379864-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1983-04-12 US disclosed
EP-0032905-A4 CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. FOLEY WILLIAM M JUN 1981-08-27 EP disclosed
EP-0032905-A1 CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS FOLEY, Jr., William M. (US) 1981-08-05 EP disclosed
US-4267295-A Polymeric compositions and hydrogels formed therefrom SYNTEX (U.S.A.) INC. (US) 1981-05-12 US disclosed
WO-1980002840-A1 CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS FOLEY W 1980-12-24 WO disclosed
US-4180308-A Contact lens SYNTEX (USA) INC. (US) 1979-12-25 US disclosed
US-4056496-A ACRYLIC CORNEAL SCIENCES, INC. (US) 1977-11-01 US disclosed
US-3966902-A HYDROXYALKYL UNSATURATED CARBOXYLATE, BOUND AL, ZN, OR ZR AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed