SCHEMBL29091900

SCHEMBL29091900

O[C@H](F)Cc1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.52
IDO1 P14902 4/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
CPA1 P15085 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
AGXT P21549 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2766584 1.00 TRPA1 (0.52) TRPA1IDO1LOXL2CPA1TAAR1
SCHEMBL28771486 1.00 TRPA1 (0.52) TRPA1IDO1LOXL2CPA1TAAR1
SCHEMBL21882278 0.82 TRPA1 (0.54) TRPA1IDO1LOXL2CPA1TAAR1
SCHEMBL27983755 0.80 TRPA1 (0.52) TRPA1IDO1LOXL2CPA1TAAR1
SCHEMBL11563760 0.79 TRPA1 (0.50) TRPA1IDO1LOXL2CPA1TAAR1
SCHEMBL23347630 0.78 TRPA1 (0.61) TRPA1IDO1LOXL2CPA1TAAR1
SCHEMBL28771432 0.78 MME (0.40) IDO1TAAR1PPARGPPARA
SCHEMBL29092065 0.78 SLC6A4 (0.54) IDO1TAAR1PPARGPPARA
SCHEMBL10397242 0.78 AOC3 (0.52) TRPA1IDO1LOXL2CPA1
SCHEMBL28771437 0.78 MME (0.40) IDO1TAAR1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539039-B Method for synthesizing chiral fluoro phenethyl alcohol by photo-enzyme catalysis 广东省科学院微生物研究所(广东省微生物分析检测中心) 2023-10-24 CN disclosed