Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 10/20 | 0.34 |
| ▸ | NPY1R | P25929 | 7/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.34 |
| ▸ | NPY2R | P49146 | 3/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 2/20 | 0.32 |
| ▸ | GGH | Q92820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638492 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL163852 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4572685 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4572687 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4572695 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30493180 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL4572697 | 0.94 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30664363 | 0.93 | FOLH1 (0.36) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| Bromomethane SCHEMBL28338901 | 0.92 | FOLH1 (0.35) | FOLH1NPY4RNPY1RNPY5RNPY2R | |
| Biguanide SCHEMBL28973152 | 0.90 | FOLH1 (0.34) | FOLH1NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940351-A | Prodrug compositions and methods of treatment | 阿奎斯蒂弗医疗股份有限公司 | 2023-10-24 | — | — | CN | disclosed |