Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301793 | 0.78 | SLC6A4 (0.53) | OPRD1TACR1 | |
| SCHEMBL13185789 | 0.77 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL306395 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3SLC6A9 | |
| SCHEMBL29299554 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3SLC6A9 | |
| SCHEMBL472213 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3SLC6A9 | |
| SCHEMBL15637079 | 0.76 | SIGMAR1 (0.47) | SIGMAR1OPRD1 | |
| SCHEMBL3011662 | 0.75 | NPC1 (0.77) | NPC1CHRM5CHRM3 | |
| Acetic Acid SCHEMBL26964860 | 0.75 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3SLC6A9 | |
| SCHEMBL4400416 | 0.75 | SIGMAR1 (0.48) | SIGMAR1NPC1OPRD1 | |
| SCHEMBL10567168 | 0.75 | CHRM5 (0.48) | SIGMAR1CHRM5CHRM3SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586354-A | Targeting GPC3 polypeptide probe and application thereof in preparation of diagnosis and treatment radiopharmaceuticals | 南方医科大学南方医院 | 2024-02-23 | — | — | CN | claimed |
| CN-117769443-A | Fibroblast activation protein inhibitor and use thereof | 3B制药有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117586354-A | Targeting GPC3 polypeptide probe and application thereof in preparation of diagnosis and treatment radiopharmaceuticals | 南方医科大学南方医院 | 2024-02-23 | — | — | CN | disclosed |
| CN-116940585-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116940586-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114341158-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2022-04-12 | — | — | CN | disclosed |