SCHEMBL29092115

SCHEMBL29092115

O=C(O)c1cccc(C2COCCN2)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.36
ALB P02768 1/20 0.34
CDC25B P30305 1/20 0.34
PRKACA P17612 1/20 0.34
PRKACG P22612 1/20 0.34
PRKACB P22694 1/20 0.34
CYP2C9 P11712 1/20 0.33
NOTUM Q6P988 1/20 0.33
OPRM1 P35372 1/20 0.32
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 4/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
TTR P02766 1/20 0.32
DHODH Q02127 3/20 0.32
PRKAB2 O43741 2/20 0.31
PRKAG1 P54619 2/20 0.31
PRKAA2 P54646 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27972715 0.81 TSHR (0.37) CTSKCDC25BPRKACAPRKACGPRKACB
SCHEMBL29032434 0.81 APEX1 (0.36) CTSKCDC25BPRKACAPRKACGPRKACB
SCHEMBL7073356 0.77 ALDH1A1 (0.39) CTSKALBCDC25BPRKACAPRKACG
SCHEMBL28839236 0.76 ALDH1A1 (0.35) CTSKPRKACAPRKACGPRKACBOPRM1
SCHEMBL28227059 0.76 PARP1 (0.37) PRKACAPRKACGPRKACBTSHRALDH1A1
SCHEMBL29239532 0.76 ALB (0.34) ALBCDC25BCYP2C9NOTUMOPRM1
SCHEMBL7674061 0.76 PARP1 (0.39) PRKACAPRKACGPRKACB
SCHEMBL27885732 0.75 PRKACA (0.36) PRKACAPRKACGPRKACB
SCHEMBL29290313 0.74 DHODH (0.36) ALDH1A1L3MBTL1LMNAMAPTDHODH
SCHEMBL4006946 0.72 ALB (0.41) ALBCDC25BCYP2C9NOTUMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206507-A Selenium-containing compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-06-18 CN disclosed
CN-116925009-A Compound containing 4-methylthio benzyl and preparation method and application thereof 中国医学科学院医药生物技术研究所 2023-10-24 CN disclosed