Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 17/20 | 0.44 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092133 | 1.00 | PDE2A (0.44) | PDE2APDE9ABRD4PTGDR2 | |
| SCHEMBL29092513 | 0.86 | BRD4 (0.43) | BRD4 | |
| SCHEMBL29092907 | 0.86 | BRD4 (0.43) | BRD4 | |
| SCHEMBL28339300 | 0.83 | KDM4E (0.42) | BRD4 | |
| SCHEMBL28339299 | 0.83 | KDM4E (0.42) | BRD4 | |
| Hydrochloric Acid SCHEMBL29092597 | 0.82 | KDM4E (0.41) | BRD4 | |
| SCHEMBL18282858 | 0.75 | PDE2A (0.49) | PDE2APDE9ABRD4PTGDR2 | |
| SCHEMBL18283158 | 0.74 | PDE2A (0.61) | PDE2A | |
| SCHEMBL18282813 | 0.74 | PDE2A (0.61) | PDE2A | |
| SCHEMBL18282811 | 0.74 | PDE2A (0.61) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582485-B | Pyrazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-13 | — | — | CN | claimed |