Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 8/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092513 | 1.00 | BRD4 (0.43) | BRD4KCNN4PNMTEPHX1CES2 | |
| SCHEMBL29092133 | 0.86 | PDE2A (0.44) | BRD4 | |
| SCHEMBL29092145 | 0.86 | PDE2A (0.44) | BRD4 | |
| SCHEMBL28339299 | 0.81 | KDM4E (0.42) | BRD4MEN1KMT2A | |
| SCHEMBL28339300 | 0.81 | KDM4E (0.42) | BRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29092597 | 0.80 | KDM4E (0.41) | BRD4MEN1KMT2A | |
| SCHEMBL28337178 | 0.71 | BRD4 (0.52) | BRD4 | |
| SCHEMBL24799276 | 0.70 | BRD4 (0.64) | BRD4 | |
| SCHEMBL377074 | 0.69 | AURKA (0.57) | PNMTEPHX1CES2 | |
| SCHEMBL11491038 | 0.68 | CES2 (0.46) | BRD4KCNN4PNMTCES2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582485-B | Pyrazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-13 | — | — | CN | claimed |