Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091968 | 0.82 | MAPT (0.49) | IGF1RAURKAMAPTMAPK1TP53 | |
| SCHEMBL25386738 | 0.76 | MAPK10 (0.41) | AURKAMAPTTP53GALR2GALR1 | |
| SCHEMBL25386961 | 0.69 | RAF1 (0.47) | IGF1RMAPTMAPK1PLK4LMNA | |
| SCHEMBL1124059 | 0.68 | HTT (0.52) | MAPTMAPK1LMNAALDH1A1GAA | |
| SCHEMBL25387217 | 0.67 | FYN (0.45) | MAPTMAPK1TP53LMNAALDH1A1 | |
| SCHEMBL25388213 | 0.67 | MAPT (0.44) | MAPTGAAMEN1KMT2A | |
| SCHEMBL5380919 | 0.66 | KMT2A (0.50) | IGF1RAURKAMAPTMAPK1TP53 | |
| SCHEMBL27875709 | 0.65 | AURKA (0.66) | AURKAMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL5402668 | 0.65 | AURKA (0.48) | IGF1RAURKAMAPTMAPK1TP53 | |
| SCHEMBL12562997 | 0.65 | PIK3CB (0.46) | MAPTMAPK1ALDH1A1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507611-A | Novel capsid assembly inhibitor | 佩勒梅德有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116507611-A | Novel capsid assembly inhibitor | 佩勒梅德有限公司 | 2023-07-28 | — | — | CN | disclosed |