Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 3/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821753 | 0.86 | AURKA (0.45) | KMT2AAURKACYP1A2AURKBKDR | |
| SCHEMBL29091968 | 0.84 | MAPT (0.49) | KMT2AMAPTKDM4ERXFP1AURKA | |
| SCHEMBL5402668 | 0.81 | AURKA (0.48) | KMT2AMAPTKDM4ERXFP1AURKA | |
| SCHEMBL5381106 | 0.81 | KMT2A (0.61) | KMT2AMAPTKDM4EAURKAMAPK10 | |
| SCHEMBL5815015 | 0.80 | AURKA (0.47) | KMT2AMAPTKDM4ERXFP1AURKA | |
| SCHEMBL5389772 | 0.80 | MAPT (0.47) | KMT2AMAPTKDM4ERXFP1AURKA | |
| SCHEMBL26938050 | 0.79 | GALR2 (0.48) | KMT2AMAPTAURKAAURKBLMNA | |
| SCHEMBL5387423 | 0.79 | AURKA (0.42) | KMT2AMAPTKDM4ERXFP1AURKA | |
| SCHEMBL5822050 | 0.79 | INSR (0.46) | KMT2AMAPTKDM4ERXFP1AURKA | |
| SCHEMBL5824056 | 0.78 | AURKA (0.48) | KMT2AMAPTKDM4ERXFP1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276501-B2 | 6-(4-substituted-anilino)pyrimidine derivatives, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2007-10-02 | — | — | US | claimed |
| US-20050222150-A1 | 6-(4-substituted-anilino)pyrimidine derivates, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2005-10-06 | — | — | US | claimed |
| US-7276501-B2 | 6-(4-substituted-anilino)pyrimidine derivatives, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2007-10-02 | — | — | US | disclosed |
| US-7276501-B2 | 6-(4-substituted-anilino)pyrimidine derivatives, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2007-10-02 | — | — | US | disclosed |
| US-7276501-B2 | 6-(4-substituted-anilino)pyrimidine derivatives, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2007-10-02 | — | — | US | disclosed |
| WO-2006137706-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM. CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |
| EP-1490358-A4 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM (KR) | 2006-04-12 | — | — | EP | disclosed |
| US-20050222150-A1 | 6-(4-substituted-anilino)pyrimidine derivates, method for preparation thereof and antiviral pharmaceutical composition comprising the same | B & C BIOPHARM (KR) | 2005-10-06 | — | — | US | disclosed |
| EP-1490358-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C Biopharm (KR) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084953-A1 | 6-(4-SUBSTITUTED-ANILINO)PYRIMIDINE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM (KR) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222150-A1 | 6-(4-substituted-anilino)pyrimidine derivates, method for preparation thereof and antiviral pharmaceutical composition comprising the same | HAVCR2, NUDT1, GART | KMT2A 4775/4885MAPT 4588/4885KDM4E 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.