Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.32 |
| ▸ | FEN1 | P39748 | 5/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615506 | 0.79 | DGAT1 (0.38) | DGAT1BRD4CREBBPALOX5APFEN1 | |
| SCHEMBL21463417 | 0.79 | DGAT1 (0.38) | DGAT1BRD4CREBBPALOX5APFEN1 | |
| SCHEMBL68020 | 0.75 | DGAT1 (0.43) | DGAT1BRD4CREBBP | |
| SCHEMBL31050029 | 0.72 | DGAT1 (0.40) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL29581588 | 0.72 | PIK3CA (0.34) | DGAT1 | |
| SCHEMBL30615511 | 0.70 | MAPT (0.40) | DGAT1BRD4CREBBPMAPT | |
| SCHEMBL21463586 | 0.70 | MAPT (0.40) | DGAT1BRD4CREBBPMAPT | |
| SCHEMBL16247668 | 0.70 | DGAT1 (0.38) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL2888150 | 0.70 | DGAT1 (0.41) | DGAT1SRCTEK | |
| SCHEMBL68598 | 0.69 | DGAT1 (0.34) | DGAT1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |