Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092815 | 0.83 | RUNX1 (0.44) | SCN8ASCN10ARUNX1TRPV1P2RY1 | |
| SCHEMBL29093339 | 0.83 | ABL1 (0.42) | MAP2K1SCN8ASCN10ARUNX1TRPV1 | |
| SCHEMBL30556734 | 0.83 | ABL1 (0.42) | MAP2K1SCN8ASCN10ARUNX1TRPV1 | |
| SCHEMBL28981537 | 0.81 | ENPP1 (0.37) | KDM4ETDP1MAPTMEN1KMT2A | |
| SCHEMBL28981729 | 0.77 | MAP2K1 (0.47) | MAP2K1SCN8ASCN10ARUNX1TRPV1 | |
| SCHEMBL29092393 | 0.77 | RUNX1 (0.45) | SCN8ASCN10ARUNX1P2RY1DHODH | |
| SCHEMBL29093349 | 0.74 | RUNX1 (0.44) | RUNX1TRPV1P2RY1DHODHKCNK3 | |
| SCHEMBL28981531 | 0.74 | RUNX1 (0.44) | SCN8ASCN10ARUNX1DHODHDRD1 | |
| SCHEMBL29092827 | 0.72 | MAP2K1 (0.46) | MAP2K1DRD1KDM4ETDP1MAPT | |
| SCHEMBL30556715 | 0.72 | MAP2K1 (0.46) | MAP2K1DRD1KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956929-B | Heterocyclic derivative, preparation method, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |