Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092816 | 0.95 | BCHE (0.35) | BCHEACHE | |
| SCHEMBL29092604 | 0.93 | BCHE (0.34) | BCHEACHE | |
| SCHEMBL27031189 | 0.88 | BACE1 (0.41) | BCHEDDB1CRBN | |
| SCHEMBL29930570 | 0.88 | BACE1 (0.41) | BCHEDDB1CRBN | |
| SCHEMBL27031231 | 0.87 | PIM1 (0.40) | BCHEACHEDDB1CRBN | |
| SCHEMBL27031119 | 0.84 | KDM2B (0.36) | BCHEACHEDDB1CRBN | |
| SCHEMBL27031242 | 0.83 | CCR3 (0.34) | BCHEACHEDDB1CRBN | |
| SCHEMBL27031148 | 0.83 | DDB1 (0.39) | BCHEACHEDDB1CRBN | |
| SCHEMBL27031092 | 0.83 | BCHE (0.33) | BCHEACHEDDB1CRBNPDCD1 | |
| SCHEMBL27031149 | 0.83 | DDB1 (0.37) | BCHEACHEDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940571-A | Benzisoxazole derivative and use thereof | 诺华股份有限公司 | 2023-10-24 | — | — | CN | disclosed |