Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930570 | 1.00 | BACE1 (0.41) | BACE1CTSDDDB1CRBNCYP2C9 | |
| SCHEMBL29930874 | 0.95 | DDB1 (0.40) | BACE1CTSDDDB1CRBNFEN1 | |
| SCHEMBL27031146 | 0.95 | DDB1 (0.40) | BACE1CTSDDDB1CRBNFEN1 | |
| SCHEMBL29930726 | 0.94 | DDB1 (0.39) | BACE1CTSDDDB1CRBN | |
| SCHEMBL27031216 | 0.94 | DDB1 (0.39) | BACE1CTSDDDB1CRBN | |
| SCHEMBL29930847 | 0.93 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL27031088 | 0.93 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL29930514 | 0.90 | DDB1 (0.41) | BACE1DDB1CRBN | |
| SCHEMBL27031107 | 0.90 | DDB1 (0.41) | BACE1DDB1CRBN | |
| SCHEMBL29092429 | 0.88 | LDHA (0.34) | DDB1CRBNBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308559-A1 | BENZISOXAZOLE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-01-24 | — | — | EP | disclosed |