Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29233382 | 0.97 | MAPT (0.50) | MAPTDAOTSHRNAPRTALDH1A1 | |
| Terephthalic Acid SCHEMBL28926617 | 0.90 | MAPT (0.57) | MAPTTSHRALDH1A1RAB9ASRD5A2 | |
| Isophthalic Acid SCHEMBL3358306 | 0.87 | KMT2A (0.44) | MAPTALDH1A1HPGDCYP2C9 | |
| Benzoic Acid SCHEMBL29006848 | 0.83 | DAO (0.40) | MAPTDAOTSHRNAPRTALDH1A1 | |
| Phthalic Acid SCHEMBL28981609 | 0.83 | ALDH1A1 (0.50) | MAPTTSHRNAPRTALDH1A1HPGD | |
| Phthalic Acid SCHEMBL30219236 | 0.83 | ALDH1A1 (0.50) | MAPTTSHRNAPRTALDH1A1HPGD | |
| Benzoic Acid SCHEMBL770049 | 0.82 | TSHR (0.64) | MAPTDAOTSHRNAPRTALDH1A1 | |
| Benzoic Acid SCHEMBL2963265 | 0.82 | TSHR (0.64) | MAPTDAOTSHRNAPRTALDH1A1 | |
| Benzoic Acid SCHEMBL5918273 | 0.82 | TSHR (0.64) | MAPTDAOTSHRNAPRTALDH1A1 | |
| Benzoic Acid SCHEMBL28469305 | 0.81 | TSHR (0.44) | DAOTSHRNAPRTALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478846-B | Carrier of catalyst with olefin polymerization catalyzing function, preparation method and application thereof, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | disclosed |