Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092886 | 1.00 | PPARG (0.34) | PPARGPPARDPPARAMAPTHPGD | |
| SCHEMBL21382371 | 0.89 | PPARG (0.33) | PPARGPPARDPPARA | |
| SCHEMBL21382373 | 0.89 | PPARG (0.33) | PPARGPPARDPPARA | |
| SCHEMBL22091388 | 0.86 | PPARG (0.33) | PPARGPPARDPPARAMAPTHPGD | |
| SCHEMBL29092372 | 0.86 | EPHX2 (0.33) | PPARGPPARDPPARAPCSK9 | |
| SCHEMBL29092371 | 0.86 | EPHX2 (0.33) | PPARGPPARDPPARAPCSK9 | |
| SCHEMBL29981698 | 0.84 | AAK1 (0.37) | PPARGPPARDPPARAMAPTHPGD | |
| SCHEMBL29981387 | 0.84 | AAK1 (0.37) | PPARGPPARDPPARAMAPTHPGD | |
| SCHEMBL28470899 | 0.84 | PPARD (0.44) | PPARGPPARDPPARARAB9A | |
| SCHEMBL29092331 | 0.84 | PPARD (0.44) | PPARGPPARDPPARARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886227-B | Novel aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions containing them | 柳韩洋行 | 2023-10-13 | — | — | CN | disclosed |