Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29092371 | 1.00 | EPHX2 (0.33) | EPHX2PPARGPPARDPPARAPCSK9 | |
| SCHEMBL22091184 | 0.86 | PCSK9 (0.33) | EPHX2PCSK9EGFRRAF1KDR | |
| SCHEMBL21382420 | 0.86 | ALDH1A1 (0.31) | PPARGPPARDPPARA | |
| SCHEMBL21382417 | 0.86 | ALDH1A1 (0.31) | PPARGPPARDPPARA | |
| SCHEMBL29092886 | 0.86 | PPARG (0.34) | PPARGPPARDPPARAPCSK9 | |
| SCHEMBL29092887 | 0.86 | PPARG (0.34) | PPARGPPARDPPARAPCSK9 | |
| SCHEMBL29092715 | 0.85 | — | — | |
| SCHEMBL29092716 | 0.85 | — | — | |
| SCHEMBL29981877 | 0.85 | — | — | |
| SCHEMBL29092331 | 0.84 | PPARD (0.44) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886227-B | Novel aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions containing them | 柳韩洋行 | 2023-10-13 | — | — | CN | disclosed |