Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 4/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646034 | 0.86 | GAA (0.51) | GAAKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL11045299 | 0.85 | GAA (0.49) | GAAKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL26079396 | 0.80 | GAA (0.50) | GAAKMT2ASMN1; SMN2L3MBTL1NAAA | |
| SCHEMBL9387072 | 0.80 | GAA (0.50) | GAAKMT2ASMN1; SMN2L3MBTL1NAAA | |
| SCHEMBL8162071 | 0.80 | GAA (0.44) | GAAKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL1982542 | 0.79 | GAA (0.49) | GAAKMT2ASMN1; SMN2L3MBTL1NAAA | |
| SCHEMBL27547194 | 0.79 | GAA (0.49) | GAAKMT2ASMN1; SMN2L3MBTL1NAAA | |
| SCHEMBL8536341 | 0.76 | GAA (0.40) | GAAKMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL16389263 | 0.76 | LMNA (0.39) | GAAKMT2AMEN1LMNA | |
| SCHEMBL8654306 | 0.75 | KMT2A (0.49) | GAAKMT2ASMN1; SMN2NAAADGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660150-B | IL-18 binding proteins (IL-18 BP) and antibodies in inflammatory diseases | AB2生物股份有限公司 | 2023-10-24 | — | — | CN | disclosed |