Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512921 | 0.80 | PDGFRB (0.78) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL5272031 | 0.78 | PDGFRB (0.51) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL20629462 | 0.77 | PDGFRB (0.63) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL5268586 | 0.77 | PDGFRB (0.53) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL24553587 | 0.77 | TSHR (0.60) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL5268641 | 0.77 | PDGFRB (0.52) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL5270352 | 0.76 | PDGFRB (0.51) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL4905240 | 0.75 | KMT2A (0.62) | KMT2AMEN1MAPTTDP1 | |
| SCHEMBL25175574 | 0.75 | MEN1 (0.64) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL6256459 | 0.74 | HRH3 (0.58) | KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491918-B | Aryl and heteroaryl substituted indole compounds | 百时美施贵宝公司 | 2023-10-24 | — | — | CN | disclosed |