Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512921 | 0.81 | PDGFRB (0.78) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL29093475 | 0.77 | PDGFRB (0.62) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL8602640 | 0.74 | KMT2A (0.64) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL30523105 | 0.74 | KMT2A (1.00) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL18058690 | 0.74 | KMT2A (0.93) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL1639878 | 0.74 | KMT2A (1.00) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL2465473 | 0.74 | KDM4E (0.64) | PDGFRBPDGFRACYP2A6CYP1A2CYP2C9 | |
| SCHEMBL29953506 | 0.73 | AXL (0.59) | PDGFRBPDGFRAKMT2AMEN1MAPT | |
| SCHEMBL20571284 | 0.73 | CYP2A6 (0.53) | TDP1CYP2A6TSHR | |
| SCHEMBL92643 | 0.73 | AXL (0.59) | PDGFRBPDGFRAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424925-A1 | NOVEL HDAC6 INHIBITORS, WITH IMPROVED SOLUBILITY AND THEIR USES | Universität Regensburg (DE) | 2019-01-09 | — | — | EP | disclosed |