SCHEMBL29093702

SCHEMBL29093702

Clc1ccc(Cn2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.73
ALDH1A1 P00352 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
MAPK10 P53779 1/20 0.59
P2RX4 Q99571 2/20 0.58
HDAC6 Q9UBN7 2/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC10 Q969S8 1/20 0.56
LMNA P02545 2/20 0.55
TP53 P04637 1/20 0.55
MAPT P10636 1/20 0.55
KDM4E B2RXH2 1/20 0.55
MEN1 O00255 1/20 0.55
USP2 O75604 1/20 0.55
POLB P06746 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616069 1.00 CYP19A1 (0.73) CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL13957035 0.91 CYP19A1 (0.86) CYP19A1CYP1A2CYP2C19P2RX4HDAC6
SCHEMBL30007452 0.85 CYP19A1 (1.00) CYP19A1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL151053 0.85 CYP19A1 (1.00) CYP19A1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL17841725 0.83 CYP19A1 (0.73) CYP19A1CYP1A2CYP2C19P2RX4HDAC6
Ammonia Solution, Strong SCHEMBL29210102 0.83 CYP19A1 (0.95) CYP19A1ALDH1A1CYP1A2CYP2C9CYP2C19
Bromide SCHEMBL28888744 0.83 CYP19A1 (0.95) CYP19A1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL9398256 0.83 CYP19A1 (0.95) CYP19A1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL28969544 0.82 HDAC3 (0.59) CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL18382517 0.82 CYP19A1 (0.70) CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290336-A Environment-friendly method for implementing debenzylation of amine compound by catalyzing molecular oxygen oxidation through semiconductor photocatalyst 大连理工大学 2024-07-05 CN disclosed
CN-116874409-A Green debenzylation method by photocatalytic molecular oxygen oxidation 大连理工大学 2023-10-13 CN disclosed