Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.68 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093970 | 1.00 | TLR8 (0.68) | TLR8TLR7KCNH2KCNA3KCNA5 | |
| SCHEMBL18109545 | 0.87 | TLR8 (0.75) | TLR8TLR7KCNH2 | |
| SCHEMBL18109542 | 0.87 | TLR8 (0.75) | TLR8TLR7KCNH2 | |
| SCHEMBL24060142 | 0.85 | TLR8 (0.71) | TLR8TLR7KCNH2 | |
| SCHEMBL29093607 | 0.82 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| SCHEMBL29093600 | 0.82 | TLR8 (0.64) | TLR8TLR7KCNH2 | |
| Selgantolimod SCHEMBL31141439 | 0.81 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| Selgantolimod SCHEMBL18109408 | 0.81 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| Selgantolimod SCHEMBL18109405 | 0.81 | TLR8 (1.00) | TLR8TLR7KCNH2 | |
| Selgantolimod SCHEMBL18109719 | 0.81 | TLR8 (1.00) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768883-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |