SCHEMBL29094

SCHEMBL29094

CC[SiH](CC)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2269619 0.79
SCHEMBL2272489 0.75
SCHEMBL2268302 0.75
SCHEMBL2271510 0.73
SCHEMBL15915908 0.72
SCHEMBL15915903 0.69
SCHEMBL16180778 0.69
SCHEMBL564706 0.67
SCHEMBL4386834 0.65 TSHR (0.35)
SCHEMBL9508339 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6800 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838372-B Triphenylethylene derivative and organic electroluminescent device comprising triphenylethylene derivative 广东省大湾区华南理工大学聚集诱导发光高等研究院 2024-05-10 CN claimed
WO-2024092420-A1 PREPARATION METHOD FOR ((2R,7AS)-2-FLUOROHEXAHYDRO-1H-PYRROLIZIN-7A-YL)METHANOL 上海皓元医药股份有限公司 2024-05-10 WO claimed
WO-2024093947-A1 PRODRUG FOR DELIVERING SIRNA INTO CELL 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
WO-2024093907-A1 LIGAND FOR DELIVERING SIRNA TO EYE AND CENTRAL NERVOUS SYSTEM 大睿生物医药科技(上海)有限公司 2024-05-10 WO claimed
EP-2991655-B1 COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-04-10 EP claimed
CN-117326956-A Tetraphenyl ethylene derivative and organic electroluminescent device comprising same 广东省大湾区华南理工大学聚集诱导发光高等研究院 2024-01-02 CN claimed
CN-117303998-A Tetraphenyl ethylene derivative and organic electroluminescent device comprising same 广东省大湾区华南理工大学聚集诱导发光高等研究院 2023-12-29 CN claimed
US-20230406878-A1 OLIGONUCLEOTIDES, REAGENTS, AND PREPARATION THEREOF BIOGEN MA INC. 2023-12-21 US claimed
CN-117105847-A Tetraphenyl ethylene derivative and organic electroluminescent device comprising same 广东省大湾区华南理工大学聚集诱导发光高等研究院 2023-11-24 CN claimed
CN-116940582-A Oligonucleotides, reagents and their preparation 渤健马萨诸塞州股份有限公司 2023-10-24 CN claimed
WO-2003080591-A1 PROCESS FOR THE PREPARATION OF 4-OXYTETRAHYDROPYRAN-2-ONES KRKA TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) 2003-10-02 WO claimed
US-6608216-B2 Preparing biaryl atropisomers; chirality transfer from stereogenic center of secondary alcohol to biaryl stereogenic axis via regioselective intramolecular migration ABBOTT LABORATORIES 2003-08-19 US claimed
US-20030073844-A1 Process for the preparation of chiral glucocorticoid receptor agents ABBOTT LABORATORIES 2003-04-17 US claimed
WO-2003002548-A1 A PROCESS FOR THE PREPARATION OF CHIRAL GLUCOCORTICOID RECEPTOR AGENTS ABBOTT LABORATORIES (US) 2003-01-09 WO claimed
EP-1091972-A1 REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2001-04-18 EP claimed
WO-2000001711-A1 REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2000-01-13 WO claimed
EP-0553107-B1 PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY PROCYON PHARM INC (US) 1999-09-29 EP claimed
US-5583235-A ALKENYLATION, CYCLIZATION SHAMAN PHARMACEUTICALS, INC. (US) 1996-12-10 US claimed
US-5164525-A SYNTHETIC PROCESS FOR FK-506 TYPE MACROLIDE INTERMEDIATES MERCK & CO., INC. (US) 1992-11-17 US claimed
EP-0405994-A2 Synthetic process for FK-506 type macrolide intermediates MERCK & CO. INC. (US) 1991-01-02 EP claimed