SCHEMBL290941

SCHEMBL290941

COc1cc(C=CC(=O)O)cc(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.67
ATM Q13315 1/20 0.67
KDM4E B2RXH2 5/20 0.62
PTGS2 P35354 3/20 0.62
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
PKM P14618 2/20 0.62
PTGS1 P23219 2/20 0.62
HTR1A P08908 1/20 0.62
HTR2C P28335 1/20 0.62
CYP1A1 P04798 5/20 0.61
CYP1B1 Q16678 4/20 0.61
BACE1 P56817 2/20 0.59
CYP1A2 P05177 3/20 0.57
CYP2D6 P10635 2/20 0.57
ABCG2 Q9UNQ0 2/20 0.56
MAPK1 P28482 2/20 0.56
ALOX15 P16050 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290940 1.00 THRB (0.67) THRBATMKDM4EPTGS2ALDH1A1
Hydrochloric Acid SCHEMBL2592367 0.98 THRB (0.65) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL10900974 0.98 THRB (0.65) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL10900978 0.98 THRB (0.65) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL4685076 0.91 BACE1 (0.73) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL4685073 0.91 BACE1 (0.73) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL12176946 0.89 THRB (0.59) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL19187093 0.89 THRB (0.59) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL3017301 0.88 THRB (0.57) THRBATMKDM4EPTGS2ALDH1A1
SCHEMBL1340085 0.88 THRB (0.57) THRBATMKDM4EPTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118421539-B Bacillus bailii E16 and application thereof as biocontrol bacteria in preventing and controlling plant diseases 海南大学三亚南繁研究院 2024-10-15 CN claimed
CN-118421539-A Bacillus bailii E16 and application thereof as biocontrol bacteria in preventing and controlling plant diseases 海南大学三亚南繁研究院 2024-08-02 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP claimed
CN-116120271-B Genipin derivative and preparation method and application thereof 广东工业大学 2023-06-20 CN claimed
CN-116120271-A Genipin derivative and preparation method and application thereof 广东工业大学 2023-05-16 CN claimed
CN-111072638-B Method for preparing AZD4547, intermediate and preparation method of intermediate 上海工程技术大学 2021-03-16 CN claimed
CN-111072638-A Method for preparing AZD4547, intermediate and preparation method of intermediate 上海工程技术大学 2020-04-28 CN claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
CN-1030681-C Improvements in or relating to avian control NAT RES DEV (GB) 1996-01-17 CN claimed
US-5196451-A Substituted cinnamamide NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1993-03-23 US claimed
EP-0321208-B1 IMPROVEMENTS IN OR RELATING TO AVIAN CONTROL NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-07-03 EP claimed
CN-1035034-A The improvement of avian control NAT RES DEV (GB) 1989-08-30 CN claimed
EP-0321208-A1 Improvements in or relating to avian control NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1989-06-21 EP claimed
US-4572803-A ENHANCED THERMAL, CHEMICAL AND PHYSICAL STABILITY ASAHI DOW LIMITED (JP) 1986-02-25 US claimed
US-4443380-A Organic europlum salt phosphor ASAHI-DOW LIMITED (JP) 1984-04-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 THRB 3311/4885ATM 1681/4885KDM4E 1567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.