Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471217 | 0.84 | PPM1B (0.46) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL8573405 | 0.84 | PPM1B (0.46) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL8571273 | 0.84 | PPM1B (0.46) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL11471218 | 0.84 | PPM1B (0.46) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL6420484 | 0.83 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL31536632 | 0.83 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL31579863 | 0.80 | PPM1B (0.39) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL29008217 | 0.79 | ALDH1A1 (0.40) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL18179612 | 0.78 | PPM1B (0.52) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL3039889 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528869-A | Amino heteroaryl kinase inhibitors | 安锐生物医药科技(广州)有限公司 | 2023-08-01 | — | — | CN | disclosed |