SCHEMBL29094374

SCHEMBL29094374

CCC(=CCc1ccccc1)c1nccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.47
CNR2 P34972 5/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
CCR1 P32246 1/20 0.36
LMNA P02545 1/20 0.36
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
PLAU P00749 2/20 0.36
F12 P00748 1/20 0.36
NCF1 P14598 1/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21182263 0.87 CYP2A6 (0.44) RAB9ACNR2CYP2A6TSHRCYP3A4
SCHEMBL29094377 0.85 RAB9A (0.44) RAB9ACNR2CYP2A6TSHRCYP3A4
SCHEMBL29094378 0.83 RAB9A (0.49) RAB9ACNR2CYP2A6TSHRCYP3A4
SCHEMBL18453504 0.82 CYP2A6 (0.46) RAB9ACNR2CYP2A6TSHRCYP3A4
SCHEMBL29094375 0.80 RAB9A (0.42) RAB9ACNR2TSHRMEN1TP53
SCHEMBL29094384 0.78 RAB9A (0.40) RAB9ACNR2TSHRMEN1TP53
SCHEMBL29094382 0.76 RAB9A (0.39) RAB9ATSHRCYP2C19MEN1TP53
SCHEMBL18950546 0.72 CYP2A6 (0.44) RAB9ACNR2CYP2A6TSHRCYP3A4
SCHEMBL3297650 0.71 CNR2 (0.52) RAB9ACNR2CYP2A6TSHRCYP3A4
SCHEMBL19134389 0.71 CYP2A6 (0.47) RAB9ACNR2CYP2A6TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730915-A Method for asymmetric catalytic synthesis of allyl chiral aza-arene derivative by using visible light and application of allyl chiral aza-arene derivative 河南工业大学 2023-09-12 CN disclosed