Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 7/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702789 | 0.90 | TNF (0.43) | CDK9CCNT1GRM5EEDRBBP4 | |
| SCHEMBL30702786 | 0.90 | TNF (0.43) | CDK9CCNT1GRM5EEDRBBP4 | |
| SCHEMBL29197644 | 0.88 | CDK9 (0.39) | CDK9CCNT1BTKMAPTPRMT5 | |
| SCHEMBL29094612 | 0.83 | PRMT5 (0.40) | CDK9CCNT1BTKMAPTPRMT5 | |
| SCHEMBL23538333 | 0.80 | PDE10A (0.44) | CDK9CCNT1GRM5EEDRBBP4 | |
| SCHEMBL29744746 | 0.80 | PDE10A (0.44) | CDK9CCNT1GRM5EEDRBBP4 | |
| SCHEMBL29279169 | 0.80 | PRMT5 (0.39) | CDK9CCNT1BTKPRMT5GRM5 | |
| SCHEMBL29744828 | 0.80 | NAMPT (0.44) | CDK9CCNT1GRM5 | |
| SCHEMBL23538491 | 0.80 | NAMPT (0.44) | CDK9CCNT1GRM5 | |
| SCHEMBL24880538 | 0.78 | PDK4 (0.46) | CDK9CCNT1BTKGRM5EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891502-A | EGFR degrading agent | 上海齐鲁制药研究中心有限公司 | 2023-10-17 | — | — | CN | disclosed |