SCHEMBL29094576

SCHEMBL29094576

OCCC1(F)CCNCC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31382536 0.98 KDM1A (0.30) KDM1A
SCHEMBL23578975 0.86
SCHEMBL21644293 0.86
SCHEMBL670786 0.79
Hydrochloric Acid SCHEMBL320981 0.77 SLC6A2 (0.32) KDM1A
SCHEMBL21872594 0.75 KDM1A (0.31) KDM1A
SCHEMBL5255004 0.74
Hydrochloric Acid SCHEMBL28904819 0.72
SCHEMBL2695845 0.72 DRD2 (0.30)
SCHEMBL12067979 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116888108-B Novel EGFR degradation agent 上海齐鲁制药研究中心有限公司 2024-04-19 CN disclosed
CN-116891502-A EGFR degrading agent 上海齐鲁制药研究中心有限公司 2023-10-17 CN disclosed
CN-116888108-A Novel EGFR degradation agent 上海齐鲁制药研究中心有限公司 2023-10-13 CN disclosed
WO-2022194269-A1 NOVEL EGFR DEGRADATION AGENT 上海齐鲁制药研究中心有限公司 2022-09-22 WO disclosed