Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702803 | 0.92 | PDK4 (0.45) | GRM5BTKPDK4PDE10A | |
| SCHEMBL29094532 | 0.83 | KHK (0.42) | GRM5PRMT5CDK9CCNT1BTK | |
| Hydrochloric Acid SCHEMBL30702787 | 0.83 | KHK (0.37) | GRM5PRMT5CDK9KHK | |
| Hydrochloric Acid SCHEMBL29094536 | 0.83 | KHK (0.37) | GRM5PRMT5CDK9KHK | |
| SCHEMBL30273891 | 0.81 | GRM5 (0.37) | GRM5PRMT5CDK9CCNT1HDAC8 | |
| SCHEMBL25169744 | 0.76 | PRMT5 (0.44) | GRM5PRMT5CDK9 | |
| SCHEMBL16107429 | 0.76 | PIM1 (0.47) | GRM5PRMT5CDK9BTKPDK4 | |
| SCHEMBL30702807 | 0.76 | NAMPT (0.41) | GRM5PRMT5BTKKHKPDK4 | |
| SCHEMBL30702795 | 0.76 | NAMPT (0.41) | GRM5PRMT5BTKKHKPDK4 | |
| SCHEMBL29197644 | 0.74 | CDK9 (0.39) | GRM5PRMT5CDK9CCNT1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891502-A | EGFR degrading agent | 上海齐鲁制药研究中心有限公司 | 2023-10-17 | — | — | CN | disclosed |