SCHEMBL2909582

SCHEMBL2909582

O=C(NC1CC1)c1cc(C(=O)NC2CC2)cc(C(=O)NC2CC2)c1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.57
NPC1 O15118 7/20 0.57
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
SMYD3 Q9H7B4 8/20 0.54
MAPT P10636 1/20 0.52
HPGD P15428 3/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2911690 0.91 KMT2A (0.61) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL2695068 0.91 KMT2A (0.66) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL2452125 0.89 NPC1 (0.60) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL2825577 0.89 SMYD3 (0.58) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL2908851 0.89 KMT2A (0.69) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL435720 0.89 KMT2A (0.69) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL2915946 0.89 KMT2A (0.69) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL9978790 0.89 KMT2A (0.69) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL9979280 0.89 KMT2A (0.69) RAB9ANPC1KMT2AMEN1SMN1; SMN2
SCHEMBL2911740 0.89 KMT2A (0.69) RAB9ANPC1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 US disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed
EP-2026965-B1 MONO- AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2010-09-01 EP disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 US disclosed
US-7479515-B2 Polypropylene resin compositions CIBA SPECIALTY CHEMICALS CORP. (US) 2009-01-20 US disclosed
US-20070170398-A1 Polypropylene resin compositions SCHMIDT HANS-WERNER 2007-07-26 US disclosed
US-7235191-B2 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
EP-1366116-B1 POLYPROPYLENE RESIN COMPOSITIONS CIBA SC HOLDING AG (CH) 2006-07-19 EP disclosed
US-20040063830-A1 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORPORATION 2004-04-01 US disclosed