Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 14/20 | 0.74 |
| ▸ | ACP1 | P24666 | 1/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522065 | 1.00 | CSNK1D (0.74) | CSNK1DACP1DYRK1ACYP2D6LRRK2 | |
| SCHEMBL3791611 | 0.84 | DYRK1A (0.78) | CSNK1DACP1DYRK1ACYP2D6LRRK2 | |
| SCHEMBL17287767 | 0.83 | CSNK1D (1.00) | CSNK1DACP1DYRK1A | |
| SCHEMBL6191383 | 0.83 | DYRK1A (0.76) | CSNK1DACP1DYRK1ACYP2D6LRRK2 | |
| SCHEMBL30522062 | 0.83 | PDPK1 (0.68) | CSNK1DDYRK1ALRRK2 | |
| SCHEMBL8348837 | 0.83 | PDPK1 (0.68) | CSNK1DDYRK1ALRRK2 | |
| SCHEMBL17287650 | 0.82 | CSNK1D (1.00) | CSNK1DACP1DYRK1A | |
| SCHEMBL30522063 | 0.81 | DYRK1A (0.72) | CSNK1DACP1DYRK1ACSNK2A2CSNK2B | |
| SCHEMBL29095935 | 0.81 | DYRK1A (0.72) | CSNK1DACP1DYRK1ACSNK2A2CSNK2B | |
| SCHEMBL29095932 | 0.81 | DYRK1A (0.68) | ACP1DYRK1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535366-B | Thiazole compound and preparation method and application thereof | 广州医科大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-116535366-A | Thiazole compound and preparation method and application thereof | 广州医科大学 | 2023-08-04 | — | — | CN | disclosed |