SCHEMBL29095977

SCHEMBL29095977

c1ccc(C(c2cccnc2)c2ccccn2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.75
SLC6A2 P23975 4/20 0.75
SLC6A4 P31645 4/20 0.75
CFTR P13569 2/20 0.69
GOPC Q9HD26 2/20 0.69
CYP19A1 P11511 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
ABCB11 O95342 1/20 0.45
LMNA P02545 1/20 0.45
ESR1 P03372 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADRA2A P08913 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
PDE4A P27815 1/20 0.45
ADRA1A P35348 1/20 0.45
OPRK1 P41145 1/20 0.45
STAT6 P42226 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30638829 1.00 SLC6A3 (0.75) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL2478933 0.93 SLC6A3 (0.65) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL3290275 0.87 SLC6A3 (1.00) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL1507962 0.85 CYP19A1 (0.73) SLC6A3SLC6A2SLC6A4CFTRGOPC
Bromide SCHEMBL30297437 0.85 SLC6A3 (0.95) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL6476580 0.82 SLC6A2 (1.00) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL10154156 0.82 SLC6A2 (0.91) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL30166037 0.82 SLC6A2 (0.91) SLC6A3SLC6A2SLC6A4CFTRGOPC
Ammonia Solution, Strong SCHEMBL6000375 0.81 SLC6A2 (0.95) SLC6A3SLC6A2SLC6A4CFTRGOPC
SCHEMBL17842425 0.79 SLC6A2 (0.48) SLC6A3SLC6A2SLC6A4CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116969879-A Heteroaryl-containing triarylmethane compound and synthesis method thereof 华北水利水电大学 2023-10-31 CN disclosed