⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40105 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL3841994 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL28290535 | 0.67 | — | — | |
| SCHEMBL3186347 | 0.67 | TSHR (0.38) | — | |
| SCHEMBL9227345 | 0.67 | — | — | |
| SCHEMBL8333138 | 0.67 | — | — | |
| SCHEMBL419791 | 0.65 | — | — | |
| SCHEMBL3923279 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL2917553 | 0.65 | — | — | |
| Acetic Acid SCHEMBL15648221 | 0.65 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226060-B1 | CEMENT FOR DENTAL APPLICATIONS | KURARAY NORITAKE DENTAL INC (JP) | 2020-03-04 | — | — | EP | disclosed |
| US-8552088-B2 | Cement for dental applications | KURARAY NORITAKE DENTAL INC. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-1791851-B1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | ASTRAZENECA AB (SE) | 2010-12-01 | — | — | EP | disclosed |
| US-20100267856-A1 | CEMENT FOR DENTAL APPLICATIONS | KURARAY MEDICAL INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2226060-A1 | CEMENT FOR DENTAL APPLICATIONS | Kuraray Medical Inc. (JP) | 2010-09-08 | — | — | EP | disclosed |
| US-20080319231-A1 | Process for the Preparation of Alkyl Phosphinates | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| EP-1791851-A1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | AstraZeneca AB (SE) | 2007-06-06 | — | — | EP | disclosed |
| US-7119189-B2 | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses | NOVARTIS AG (CH) | 2006-10-10 | — | — | US | disclosed |
| WO-2006031180-A1 | PROCESS FOR PREPARATION OF ALKYL PHOSPHINATES | ASTRAZENECA AB (SE) | 2006-03-23 | — | — | WO | disclosed |
| EP-0885237-B1 | OLIGONUCLEOTIDE ANALOGUES | ISIS PHARMACEUTICALS INC (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20020091250-A1 | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses | NOVARTIS AG (CH) | 2002-07-11 | — | — | US | disclosed |
| US-6087490-A | Dinucleotide and oligonucleotide analogues | NOVARTIS AG (CH) | 2000-07-11 | — | — | US | disclosed |
| US-5952478-A | Intermediates for dinucleotide and oligonucleotide analogues | NOVARTIS FINANCE CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0885237-A1 | OLIGONUCLEOTIDE ANALOGUES | Novartis AG (CH) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997035869-A1 | DINUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES | NOVARTIS AG (CH) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997032887-A1 | OLIGONUCLEOTIDE ANALOGUES | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |
| EP-0778843-A1 | INTERMEDIATES FOR DINUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES | Novartis AG (CH) | 1997-06-18 | — | — | EP | disclosed |
| US-5508270-A | Nucleoside phosphinate compounds and compositions | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1996008503-A1 | INTERMEDIATES FOR DINUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES | NOVARTIS AG (CH) | 1996-03-21 | — | — | WO | disclosed |
| EP-0614906-A1 | Mononucleotide analogues and intermediates therefor | CIBA-GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |