Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096551 | 1.00 | MEN1 (0.50) | MEN1KMT2AL3MBTL1ABL1ABCB1 | |
| SCHEMBL29096561 | 0.90 | MEN1 (0.46) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL29096560 | 0.90 | MEN1 (0.46) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL29096535 | 0.89 | ERN1 (0.45) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL29096531 | 0.89 | ERN1 (0.45) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL29096521 | 0.88 | CA1 (0.43) | MEN1KMT2AL3MBTL1ABL1ABCB1 | |
| SCHEMBL29096524 | 0.88 | CA1 (0.43) | MEN1KMT2AL3MBTL1ABL1ABCB1 | |
| SCHEMBL29096542 | 0.84 | MEN1 (0.45) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL29096538 | 0.84 | MEN1 (0.45) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL29096536 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AL3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |