Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096566 | 1.00 | EGFR (0.39) | EGFRABL1ABL2FBP1AR | |
| SCHEMBL29096554 | 0.83 | MAPT (0.41) | EGFRABL1ABL2KDM4EMAPT | |
| SCHEMBL29096555 | 0.83 | MAPT (0.41) | EGFRABL1ABL2KDM4EMAPT | |
| SCHEMBL29096564 | 0.82 | HCAR3 (0.45) | KDM4EMAPTHTTERN1POLB | |
| SCHEMBL29096543 | 0.82 | ERN1 (0.59) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL29096559 | 0.82 | ERN1 (0.49) | EGFRABL1ABL2FBP1KDM4E | |
| SCHEMBL29096540 | 0.82 | ERN1 (0.59) | KDM4EMAPTHTTMEN1KMT2A | |
| SCHEMBL29096570 | 0.82 | ERN1 (0.49) | EGFRABL1ABL2ARKDM4E | |
| SCHEMBL29096558 | 0.82 | ERN1 (0.49) | EGFRABL1ABL2FBP1KDM4E | |
| SCHEMBL29096568 | 0.82 | ERN1 (0.49) | EGFRABL1ABL2ARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693552-A | Polycyclic dihydrobenzofuran compound and preparation method thereof | 浙江大学 | 2023-09-05 | — | — | CN | disclosed |