Methacrylic Acid

Methacrylic Acid

SCHEMBL2909657

C=C(C)C(=O)O.CC(=Cc1ccccc1)C(=O)O

nearest known ligand 0.84

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.84
HTT P42858 1/20 0.53
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
AKR1C1 Q04828 1/20 0.47
DHODH Q02127 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RECQL P46063 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
APEX1 P27695 4/20 0.45
TBXAS1 P24557 2/20 0.44
FBP1 P09467 1/20 0.44
PKM P14618 1/20 0.44
MAPK1 P28482 1/20 0.44
GLA P06280 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL9576992 0.94 AKR1C3 (0.75) AKR1C3HTTALDH1A1TSHRAKR1C1
Methacrylic Acid SCHEMBL28161780 0.93 AKR1C3 (0.72) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL41906 0.92 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL581982 0.92 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL37034 0.92 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL16568719 0.92 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRAKR1C1
Ammonia Solution, Strong SCHEMBL6327037 0.90 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRAKR1C1
Acetic Acid SCHEMBL6897109 0.90 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL27719681 0.90 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRAKR1C1
Hydrochloric Acid SCHEMBL9445639 0.90 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRAKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2079764-B1 METHOD FOR PRODUCING SILYL TELECHELIC POLYMERS EVONIK ROEHM GMBH (DE) 2010-08-11 EP disclosed
EP-1051961-B1 Bonding compositions for dental use KURARAY CO (JP) 2006-02-22 EP disclosed