Methacrylic Acid

Methacrylic Acid

SCHEMBL9576992

C=C(C)C(=O)O.CC(=Cc1ccccc1)C(=O)O.CC=C(C)C(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.75
HTT P42858 1/20 0.49
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
DHODH Q02127 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.43
AKR1C1 Q04828 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
RECQL P46063 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
APEX1 P27695 5/20 0.41
TBXAS1 P24557 2/20 0.41
PKM P14618 1/20 0.41
MAPK1 P28482 1/20 0.41
FBP1 P09467 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL2909657 0.94 AKR1C3 (0.84) AKR1C3HTTALDH1A1TSHRDHODH
SCHEMBL8850430 0.93 AKR1C3 (0.88) AKR1C3HTTALDH1A1TSHRDHODH
SCHEMBL41906 0.87 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRDHODH
SCHEMBL16568719 0.87 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRDHODH
SCHEMBL581982 0.87 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRDHODH
SCHEMBL37034 0.87 AKR1C3 (1.00) AKR1C3HTTALDH1A1TSHRDHODH
Styrene SCHEMBL5669174 0.86 AKR1C3 (0.53) AKR1C3HTTALDH1A1TSHRAKR1C1
Acetic Acid SCHEMBL6897109 0.85 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRDHODH
Ammonia Solution, Strong SCHEMBL6327037 0.85 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRDHODH
Hydrochloric Acid SCHEMBL9445639 0.85 AKR1C3 (0.95) AKR1C3HTTALDH1A1TSHRDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326938-B1 Impact-modified polycarbonate ROEHM GMBH (DE) 1993-12-22 EP disclosed
EP-0326938-A2 Impact-modified polycarbonate RÖHM GMBH (DE) 1989-08-09 EP disclosed