Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096870 | 1.00 | PTPRA (0.50) | PTPRAFDPSPARP10GRIN2DGRIN3B | |
| SCHEMBL375856 | 0.76 | SRR (0.47) | SMN1; SMN2LMNAPTGS1CYP1A2CYP2D6 | |
| SCHEMBL28432031 | 0.76 | SRR (0.47) | SMN1; SMN2LMNAPTGS1CYP1A2CYP2D6 | |
| SCHEMBL28435578 | 0.76 | SRR (0.47) | SMN1; SMN2LMNAPTGS1CYP1A2CYP2D6 | |
| SCHEMBL6679211 | 0.74 | PTPRA (0.46) | PTPRAFDPSPARP10GRIN2DGRIN3B | |
| SCHEMBL2187235 | 0.74 | PTPRA (0.59) | PTPRAFDPSPARP10GRIN2DGRIN3B | |
| SCHEMBL27761201 | 0.74 | PTPRA (0.59) | PTPRAFDPSPARP10GRIN2DGRIN3B | |
| SCHEMBL5246665 | 0.73 | MEN1 (0.42) | PARP10SMN1; SMN2LMNASLC6A2ALDH1A1 | |
| SCHEMBL14796604 | 0.72 | PTPRA (0.57) | PTPRAFDPSPARP10GRIN2DGRIN3B | |
| SCHEMBL10250742 | 0.72 | PTPRA (0.57) | PTPRAFDPSPARP10GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072207-B | Bicyclic compounds | 维瓦斯治疗公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |