Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.52 |
| ▸ | PGR | P06401 | 13/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | IL6 | P05231 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447415 | 0.89 | NR3C1 (0.66) | NR3C1PGRNR3C2CYP3A4IL6 | |
| SCHEMBL292122 | 0.80 | NR3C1 (0.67) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL27754122 | 0.79 | NR3C1 (0.57) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL292779 | 0.78 | NR3C1 (0.64) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL1635587 | 0.78 | NR3C1 (0.65) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL1931038 | 0.77 | NR3C1 (0.52) | NR3C1PGRNR3C2CYP3A4IL6 | |
| SCHEMBL293443 | 0.77 | NR3C1 (0.81) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL5822914 | 0.76 | NR3C1 (0.49) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL27754151 | 0.75 | NR3C1 (0.61) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL292311 | 0.74 | NR3C1 (0.59) | NR3C1PGRNR3C2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049112-B1 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | BAUSCH & LOMB (US) | 2012-03-14 | — | — | EP | disclosed |