Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665346 | 0.85 | FFAR4 (0.42) | KDM4EALDH1A1KMT2A | |
| SCHEMBL26615214 | 0.85 | FFAR4 (0.42) | KDM4EALDH1A1KMT2A | |
| SCHEMBL26615150 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL30665395 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL29097328 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2650529 | 0.67 | TRPV1 (0.59) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL26615181 | 0.66 | ALDH1A1 (0.46) | HPGDSMN1; SMN2KDM4EL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28760541 | 0.66 | TRPV1 (0.58) | KDM4EALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL12316591 | 0.65 | GRM5 (0.45) | HPGDSMN1; SMN2ALDH1A1KCNH2SCN3A | |
| SCHEMBL26615189 | 0.64 | ALDH1A1 (0.37) | HPGDKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947713-A | Ring-merging compound and application thereof | 中国科学院上海药物研究所 | 2023-10-27 | — | — | CN | disclosed |