Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912128 | 0.95 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL2910577 | 0.90 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL7290692 | 0.90 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL12786969 | 0.86 | GABRA1 (0.69) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL2904981 | 0.85 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL7292036 | 0.85 | GABRA1 (0.59) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL7291362 | 0.85 | GABRA1 (0.59) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL3720055 | 0.85 | GABRA1 (0.67) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL10519075 | 0.84 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3CYP1A2 | |
| SCHEMBL13930267 | 0.82 | GABRA1 (0.67) | GABRA1GABRB2GABRB1GABRA3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |
| US-20090054411-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | US | disclosed |
| EP-2010496-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007119046-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054411-A1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | CSF1R, CSF3R, FLT3 | GABRA1 1632/4885GABRB2 1840/4885GABRB1 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.