Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199299 | 0.86 | ESR2 (0.53) | MRGPRX4HPGDSMN1; SMN2USP2CHRM4 | |
| SCHEMBL29097820 | 0.86 | ESR2 (0.53) | MRGPRX4HPGDSMN1; SMN2USP2CHRM4 | |
| SCHEMBL30474301 | 0.81 | ERCC1 (0.45) | HPGDSMN1; SMN2PTGDR2ESR1ESR2 | |
| SCHEMBL29098093 | 0.81 | HRH3 (0.47) | S1PR1S1PR5PREP | |
| SCHEMBL29098088 | 0.79 | HRH3 (0.53) | S1PR1S1PR5ALDH1A1 | |
| SCHEMBL29390456 | 0.77 | ESR1 (0.50) | HPGDSMN1; SMN2ESR1ESR2KMT2A | |
| SCHEMBL13623452 | 0.77 | ESR1 (0.50) | HPGDSMN1; SMN2ESR1ESR2KMT2A | |
| SCHEMBL29098068 | 0.75 | MAOB (0.51) | MRGPRX4S1PR1S1PR5KMT2A | |
| SCHEMBL29097811 | 0.74 | HRH3 (0.44) | S1PR1ESR1ESR2L3MBTL1 | |
| SCHEMBL22981196 | 0.74 | ESR1 (0.43) | HPGDSMN1; SMN2MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |