Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR1E | P28566 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098070 | 0.86 | MAPKAPK2 (0.33) | MAPKAPK2MAPK1HTR2AHTR2CMAPKAPK5 | |
| SCHEMBL30829407 | 0.79 | ESR2 (0.43) | MAPKAPK2KDM1A | |
| SCHEMBL30829412 | 0.79 | ESR2 (0.43) | MAPKAPK2KDM1A | |
| SCHEMBL29244507 | 0.78 | MAPK1 (0.34) | MAPKAPK2MAPK1MAPKAPK5HTR2BHTR1A | |
| SCHEMBL8470413 | 0.75 | CA1 (0.43) | MAPKAPK2KDM1A | |
| SCHEMBL28970118 | 0.75 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL29097871 | 0.72 | DRD2 (0.49) | DRD4KDM1A | |
| SCHEMBL3283792 | 0.71 | TSHR (0.38) | MAPKAPK2MAPKAPK5DRD4HTR5A | |
| SCHEMBL7694988 | 0.70 | TSHR (0.60) | SLC6A4 | |
| SCHEMBL30829405 | 0.70 | TSHR (0.60) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |