Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30198766 | 1.00 | MAOB (0.54) | MAOBASIC3MAPTNR4A2POLB | |
| SCHEMBL30199485 | 0.86 | MAOB (0.55) | MAOBMAOAS1PR1 | |
| SCHEMBL29098086 | 0.86 | MAOB (0.55) | MAOBMAOAS1PR1 | |
| Hydrochloric Acid SCHEMBL29098075 | 0.85 | MAOB (0.54) | MAOBMAOAS1PR1 | |
| Hydrochloric Acid SCHEMBL30199460 | 0.85 | MAOB (0.54) | MAOBMAOAS1PR1 | |
| SCHEMBL30199170 | 0.85 | MAOB (0.56) | MAOBNR4A2MAOA | |
| SCHEMBL29097880 | 0.85 | MAOB (0.56) | MAOBNR4A2MAOA | |
| SCHEMBL30488232 | 0.84 | MAOB (0.60) | MAOBMAPTNR4A2POLBHTT | |
| SCHEMBL29474892 | 0.82 | HRH3 (0.59) | MAOBMAOA | |
| SCHEMBL3503754 | 0.82 | HRH3 (0.59) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |