Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199600 | 1.00 | NR1H2 (0.52) | NR1H2ESR2F10MMP13MMP2 | |
| SCHEMBL29097926 | 0.86 | F10 (0.51) | F10MMP13ADAM17MMP1 | |
| SCHEMBL6187651 | 0.83 | F10 (0.74) | NR1H2F10 | |
| SCHEMBL30199547 | 0.83 | NR1H2 (0.55) | NR1H2ESR2F10MAPK1GPR119 | |
| SCHEMBL30199503 | 0.83 | ESR2 (0.56) | NR1H2ESR2MAPK1HDAC8 | |
| SCHEMBL29097854 | 0.83 | ESR2 (0.56) | NR1H2ESR2MAPK1HDAC8 | |
| SCHEMBL30199064 | 0.83 | NR1H2 (0.55) | NR1H2ESR2MAPK1GPR119 | |
| SCHEMBL30199590 | 0.82 | NR1H2 (0.60) | NR1H2ESR2MAPK1HDAC8 | |
| SCHEMBL29098128 | 0.81 | GPR119 (0.58) | NR1H2ESR2F10MAPK1GPR119 | |
| SCHEMBL30199228 | 0.81 | GPR119 (0.58) | NR1H2ESR2F10MAPK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |