Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL29098179 | 1.00 | CYP1A2 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Adipic Acid SCHEMBL29021414 | 0.98 | CYP1A2 (0.61) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Adipic Acid SCHEMBL29021417 | 0.98 | CYP1A2 (0.61) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Sebacic Acid SCHEMBL28321739 | 0.98 | CYP1A2 (0.61) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Hexanoate SCHEMBL3414518 | 0.92 | AKR1B1 (0.61) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Octanoic Acid SCHEMBL3414539 | 0.90 | GPR84 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Stearic Acid SCHEMBL7718978 | 0.90 | GPR84 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Dodecanoate SCHEMBL28165247 | 0.90 | GPR84 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Heptanoate SCHEMBL3411704 | 0.90 | GPR84 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Valeric Acid SCHEMBL3416722 | 0.90 | CYP1A2 (0.57) | CYP1A2MAPK1SMN1; SMN2TSHRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112551543-B | Method for preparing IZM-2 zeolite in the presence of mixture of nitrogen-containing organic structuring agent in hydroxide and bromide form | IFP 新能源公司 | 2023-11-03 | — | — | CN | disclosed |