⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536219 | 0.73 | — | — | |
| SCHEMBL3317451 | 0.71 | — | — | |
| SCHEMBL1148901 | 0.71 | — | — | |
| SCHEMBL1825 | 0.69 | — | — | |
| SCHEMBL11700212 | 0.69 | — | — | |
| SCHEMBL128361 | 0.69 | — | — | |
| SCHEMBL10979113 | 0.69 | — | — | |
| SCHEMBL9753838 | 0.67 | THRB (0.32) | — | |
| SCHEMBL9119600 | 0.65 | — | — | |
| SCHEMBL3317222 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | claimed |
| EP-0605638-B1 | METAL ALKOXIDES | UNIV FLORIDA STATE (US) | 1999-09-01 | — | — | EP | claimed |
| US-20240239774-A1 | SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240199602-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-20 | — | — | US | disclosed |
| WO-2024123978-A1 | IONIZABLE LIPIDS WITH MALONATE TAILS | MODERNATX, INC. (US) | 2024-06-13 | — | — | WO | disclosed |
| US-20240181067-A1 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-06 | — | — | US | disclosed |
| EP-4377306-A1 | ROCK2 INHIBITORS AND USES THEREOF | President and Fellows of Harvard College (US) | 2024-06-05 | — | — | EP | disclosed |
| US-20240174637-A1 | DEGRADERS OF GRK2 AND USES THEREOF | PIIZZI GRAZIA (US) | 2024-05-30 | — | — | US | disclosed |
| US-20240174616-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20060128669-A1 | Heterocyclic compounds having inhibitory activity against hiv integrase | SHIONOGI & CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1541558-A1 | HETEROCYCLIC COMPOUND HAVING HIV INTEGRASE INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20040229909-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-20040127708-A1 | Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | disclosed |
| EP-1375486-A1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0690853-A4 | TAXANES PREPARED BY BETA-LACTAMS AND AMMONIUM ALKOXIDES | UNIV FLORIDA STATE (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0690853-A1 | TAXANES PREPARED BY BETA-LACTAMS AND AMMONIUM ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994021623-A1 | TAXANES PREPARED BY BETA-LACTAMS AND AMMONIUM ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1994-09-29 | — | — | WO | disclosed |